A Systematic Review of the Markers of Severity in Acute Respiratory Infections to Inform Primary Care Surveillance.

ABSTRACT:

Background

Primary care computerised medical records (CMR) are used to report the incidence of acute respiratory infections (ARI) for public health surveillance. These systems could increase their utility by also reporting population-level severity of ARI; however, this is rarely done.

Objectives

To identify candidate markers of ARI severity suitable for use in primary care CMR-based surveillance.

Methods

We undertook a systematic review of bibliographic databases and grey literature. Eligible studies reported characteristics for > 500 patients with ARI, severe ARI, influenza-like illness or suspected COVID-19. Studies had to report at least one potential marker of severity. A panel of clinical primary care informaticians reviewed candidate severity markers and assess

SUBMITTER: Elson WH 

PROVIDER: S-EPMC12550406 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature