HPV-DNA testing from self-sampled menstrual blood using M-strip: A proof-of-concept study on feasibility & acceptance of a novel biosampling method.

ABSTRACT: Background & objectives Screening for cervical cancer by self-sampling appears more acceptable to women and has the potential to boost screening uptake, which is dismal at present in India. Studies have shown that menstrual blood (MB) provides equivalent results to cervical smear for Human Papillomavirus (HPV)-Deoxyribonucleic acid (DNA) testing, but sample collection needs standardization. This study explored the feasibility and acceptance of self-sampling using 'M-strip' for high-risk HPV DNA (hr-HPV DNA) testing from MB. Methods One hundred and eleven women aged 30-50 yr without a previous diagnosis of pre-cancer or cancer used the M-strip to collect the MB sample. The strip was peeled off the sanitary pad after use, sent in a zip-lock pouch, and tested for high-risk human papillomaviru

SUBMITTER: Chandra S 

PROVIDER: S-EPMC12550441 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature