Efficacy and safety of microaxial flow pump in infarct-related cardiogenic shock: a meta-analysis.

ABSTRACT:

Introduction

Data regarding mechanical circulatory support with a microaxial flow pump (Impella) in patients with myocardial infarction complicated by cardiogenic shock are limited.

Methods

PubMed/Medline, Embase, and the Cochrane Library were used to search for randomized controlled trials (RCTs) from inception to 16 June 2024. Risk ratios (RRs) were pooled with corresponding 95% confidence intervals (CIs) using the random effects model.

Results

Four RCTs were included. The pooled analysis demonstrated a significantly reduced risk of all-cause death in patients with the use of a microaxial flow pump at 6-month follow-up (RR = 0.80; 95% CI: 0.67 to 0.97) and cardiac death (RR = 0.68; 95% CI: 0.49 to 0.94) as compared to the control group. However, the use of a microax

SUBMITTER: Hussain R 

PROVIDER: S-EPMC12550693 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature