Associations between Progression of Retinal Pigment Epithelial and Outer Retinal Atrophy and Choroidal Thickness: A 2-Year observation.

ABSTRACT:

Purpose

To evaluate the clinical course of retinal pigment epithelial and outer retinal atrophy (RORA) with best-corrected visual acuity (BCVA) and risk factors for rapid progression to explore the pathogenesis.

Design

Retrospective observational study.

Subjects

Data on eyes with fovea-involved RORA associated with age-related macular degeneration were collected over time from 10 hospitals in Japan.

Methods

Data on ophthalmic examination, BCVA, and OCT images were analyzed.

Main outcome measures

Relationships between changes in BCVA and extents of RORA and outer plexiform layer (OPL) deterioration and their associations with central choroidal thickness (CCT) and pachychoroid characteristics at baseline were evaluated.

Results

Of the 53 eyes of 53

SUBMITTER: Nagai N 

PROVIDER: S-EPMC12550781 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature