Diagnostic and Prognostic Potential of Tetranectin in Heart Failure and Cardiovascular Disease: A Systematic Review.

ABSTRACT:

Background

Tetranectin (CLEC3B), a plasminogen-binding protein involved in fibrinolysis and tissue remodeling, has been increasingly studied as a potential diagnostic and prognostic biomarker in cardiovascular disease (CVD). This review synthesizes current evidence on its clinical utility across heart failure (HF), coronary artery disease (CAD), and related conditions.

Objectives

To systematically evaluate and synthesize published clinical evidence on the diagnostic and prognostic value of tetranectin in cardiovascular diseases.

Methods

A systematic search of PubMed, Google Scholar, and Scopus (January 2010-June 2025) identified original human studies examining associations between tetranectin (CLEC3B) and cardiovascular diseases, including heart failure, coronary art

SUBMITTER: Vulciu PA 

PROVIDER: S-EPMC12550903 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature