Serum metabolomics reveal the mechanisms by which fermented brewer's spent grains promote intestinal development in white-feathered broilers.

ABSTRACT: This study aimed to investigate the effects of wet-fermented brewer's grains (WFBGs) on gut development and serum metabolism in white-feathered broilers. A total of 192 one-day-old male broilers (initial body weight: 36.46 ± 0.93 g) were randomly assigned to two treatment groups: the control group (0% WFBGs) and the experimental group (20% WFBG inclusion), with 6 replicates of 16 birds per replicate. The results of intestinal morphological parameters, quantified using ImageJ software after hematoxylin-eosin (HE) staining, showed that compared with the control group, broilers fed a diet supplemented with 20% WFBGs had significantly improved duodenal development. Specifically, the duodenal villus height (VH) increased by 10.2% (p < 0.05), and the villus height-to-crypt depth ratio (VH

SUBMITTER: Li Y 

PROVIDER: S-EPMC12551227 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature