Primordial germ cell specification and early developmental cell states in Pacific oyster.

ABSTRACT:

Background

Primordial germ cells (PGCs) are the precursor cells of gametes and pivotal in understanding reproductive and developmental biology. Importantly, having a thorough understanding of PGC specification is leading to critical advances in sterility induction in aquaculture species. In shellfish, however, the ability to develop these approaches is hampered by the lack of information available regarding germ cell specification. The goal of this study was to identify genes uniquely expressed in these earliest germ cells of the economically and ecologically important bivalve mollusc, the Pacific oyster (Crassostrea (Magallana) gigas).

Results

To capture specification of the PGCs - which represent a rare cell type - during embryonic development, we analyzed single-cell tran

SUBMITTER: Gavery MR 

PROVIDER: S-EPMC12551290 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature