"Hybrid exercise training improves liver steatosis and inflammation in a randomized trial of sedentary, obese women with non-alcoholic fatty liver disease".

ABSTRACT:

Background

Non-alcoholic fatty liver disease (NAFLD) represents a significant and escalating public health challenge, particularly in obese, sedentary populations. Hybrid exercise training, integrating electrical muscle stimulation (EMS) with voluntary muscle contractions, offers a novel, low-impact therapeutic modality; however, its clinical efficacy remains underexplored.

Objectives

This randomized controlled trial investigated the clinical efficacy of hybrid exercise training in improving hepatic steatosis, liver enzyme profiles, systemic inflammation, and metabolic health in sedentary, obese, middle-aged women with NAFLD.

Methods

Thirty women with ultrasound-confirmed grade 2-3 NAFLD were randomized to either six weeks of hybrid exercise training (n = 15) or lifes

SUBMITTER: Mohammadzadeh NZ 

PROVIDER: S-EPMC12551317 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature