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Prevalence and risk factors of paediatric acute ischaemic stroke: a systematic review and meta-analysis protocol.


ABSTRACT:

Introduction

Paediatric acute ischaemic stroke (AIS) is a rare but severe neurological condition, often leading to long-term disability and considerable societal burden. Compared with adults, paediatric AIS exhibits distinct clinical characteristics and aetiologies, making early identification and prevention more challenging. This study aims to systematically review the prevalence and risk factors of paediatric AIS, providing a comprehensive evidence base for clinical prevention and management.

Methods and analysis

A systematic search will be conducted across major databases, including PubMed, Embase, Web of Science and Cochrane Library, from inception to August 2025. We will include observational studies reporting on the prevalence or risk factors of paediatric AIS. Two ind

SUBMITTER: Wang P 

PROVIDER: S-EPMC12551465 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature