Efficacy and safety of dexamethasone in postoperative recovery following hysterectomy: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Hysterectomy, a common surgical procedure, is frequently associated with moderate-to-severe postoperative pain and a high incidence of postoperative nausea and vomiting (PONV). Dexamethasone, a corticosteroid, may help alleviate these symptoms; however, existing evidence is largely drawn from mixed surgical populations and does not specifically address its efficacy and safety in hysterectomy patients. This meta-analysis provides a focused and updated synthesis of randomised controlled trials (RCTs) in this population, incorporating time-stratified pain outcomes and subgroup analyses by dose, surgical approach, timing and route of administration to evaluate the role of dexamethasone in postoperative recovery.

Design

Systematic review and meta-analysis using the Gra

SUBMITTER: Inam K 

PROVIDER: S-EPMC12551471 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature