Mating status drives fitness trade-offs in exercised female Drosophila.

ABSTRACT: Regular physical exercise has been shown to improve physical and psychological well-being through a variety of mechanisms; however, the degree to which different individuals respond to exercise varies depending on sex and genetic factors. Drosophila has been used as a model organism to further understand the molecular mechanisms that underlie exercise adaptation. Essential for flies' ability to adapt to exercise, octopamine is a hormone and neurotransmitter found in invertebrates that is analogous to norepinephrine. Interestingly, octopamine is also crucial for female post-mating responses, and no studies to date have explored the interaction between exercise response and reproductive state in females. Here, we investigated the sexual dimorphism in exercise response by exercising male and

SUBMITTER: Backlund AE 

PROVIDER: S-EPMC12551838 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature