Understanding barriers to adjuvant therapy in resected non-small cell lung cancer: A multicenter analysis.

ABSTRACT:

Objectives

To investigate variables associated to not receiving adjuvant therapy in patients with resected pathological IB-IIIA NSCLC from a national registry.

Methods

Patients who had lung resections were analyzed retrospectively for stages IB-III from 2009-2023, sourced from a multicentre registry. Uni/Multivariable logistic regression was performed, and a predictive tool was created to predict adjuvant therapy probability and cut-off values were determined through ROC analysis. The model's discrimination, performance and fit were evaluated using AUC-ROC, sensitivity/specificity and Hosmer-Lemeshow test respectively.

Results

Of the 427 patients analyzed, the mean age was 65.4 years and 83.1% were treated under public insurance. 38.4% of patients received adjuvant ch

SUBMITTER: D'Ambrosio PD 

PROVIDER: S-EPMC12552094 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature