Evaluation of circulating lymphocyte subsets in children with attention-deficit hyperactivity disorder.

ABSTRACT:

Background

Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder in children, increasingly associated with immune system dysregulation. Emerging evidence suggests that alterations in circulating immune cells, particularly lymphocyte subsets, may reflect neuroinflammatory processes involved in ADHD pathophysiology. However, the precise immunophenotypic characteristics of peripheral lymphocytes in children with ADHD remain poorly defined. While immune biomarkers such as cytokines have been studied, their clinical utility is limited. In contrast, flow cytometric profiling of lymphocyte subpopulations offers a practical tool for immune monitoring. Here, we investigated the distribution of peripheral lymphocyte subsets in drug-naïve children with ADH

SUBMITTER: Zeng J 

PROVIDER: S-EPMC12552186 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature