Nicotine replacement therapy during the acute phase of aneurysmal subarachnoid hemorrhage.

ABSTRACT:

Background

Many patients who suffer an aneurysmal subarachnoid hemorrhage (aSAH) are active smokers that may experience nicotine withdrawal following hospital admission. Nicotine replacement therapy (NRT) could alleviate abstinence and delirium but may have unwanted side-effects. Cerebral vasospasm (VS) is a feared complication of aSAH that can worsen outcome. The impact of NRT on VS, complications and outcome is still not fully delineated.

Methods

Retrospective study using anonymized data from a prospective quality registry. Patients smoking status, age, sex, comorbidities, along with aSAH severity were registered. Smokers were dichotomized into non-NRT and NRT groups depending on whether they had received a nicotine patch or not and subdivided into light smokers (≤ 10 ciga

SUBMITTER: Ghafaji H 

PROVIDER: S-EPMC12552259 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature