Prognostic value of baseline body composition parameters from ¹⁸F-FDG PET/CT in angioimmunoblastic T-cell lymphoma patients.

ABSTRACT: This retrospective study investigated preliminarily the prognostic value of body composition parameters derived from baseline ¹⁸F-FDG PET/CT in angioimmunoblastic T-cell lymphoma (AITL) patients. We included 94 treatment-naïve AITL patients diagnosed by histopathology. Based on the axial CT images of the third lumbar vertebra, the areas of skeletal muscle (SM), visceral adipose tissue (VAT), and subcutaneous adipose tissue (SAT) were semi-automatically delineated and standardized to finally obtain SM index (SMI), VAT index (VATI), and SAT index (SATI). Body composition density characterized by CT attenuation was obtained, including SM density (SMD), VAT density (VATD), and SAT density (SATD). Besides, the maximum standardized uptake value (SUVmax), total metabolic tumor volume (

SUBMITTER: Gong H 

PROVIDER: S-EPMC12552394 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature