Surgical management of intrathyroidal parathyroid adenoma with nodular goiter: a case report highlighting SPECT/CT localization.

ABSTRACT:

Background

Intrathyroidal parathyroid adenomas (ITPAs) represent a rare subset of ectopic parathyroid glands, accounting for approximately 1-6% of cases. Their preoperative diagnosis remains a significant clinical challenge, as they are frequently misdiagnosed as thyroid nodules on conventional imaging such as ultrasonography and computed tomography (CT). This diagnostic difficulty is compounded in patients with concurrent thyroid pathology, such as nodular goiter. This case report aims to highlight the critical role of dual-phase technetium-99m-methoxyisobutylisonitrile (^99mTc-MIBI) single-photon emission computed tomography/computed tomography (SPECT/CT) in achieving accurate preoperative localization and facilitating successful surgical management in such complex scen

SUBMITTER: Xu L 

PROVIDER: S-EPMC12552548 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature