Diverging spatiotemporal trajectories of thyroid cancer incidence and mortality in reproductive-age women: a socio-demographic index stratified analysis of GBD 2021 data.

ABSTRACT:

Background

Thyroid cancer ranks among the most rapidly increasing endocrine malignancies worldwide, with a particularly disproportionate health burden observed in women of reproductive age. This study aimed to comprehensively assess the global, regional, and national trends in thyroid cancer burden among women aged 15-49 years from 1990 to 2021, and to explore disparities by socio-demographic index (SDI) level.

Methods

Utilizing data from the Global Burden of Disease (GBD) Study 2021, this study assessed the burden of thyroid cancer among women aged 15-49 between 1990 and 2021 and examined its association with SDI levels. Key indicators-including age-standardized incidence rate (ASIR), mortality rate (ASMR), and disability-adjusted life years rate (ASDR)-were analyzed alongs

SUBMITTER: Liu W 

PROVIDER: S-EPMC12552552 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature