Efficacy of postoperative thyroid-stimulating hormone inhibition therapy in differentiated thyroid cancer in China: a systematic literature review and meta-analysis.

ABSTRACT:

Background

Thyroid-stimulating hormone (TSH) suppression therapy after surgery is recommended for patients with differentiated thyroid cancer (DTC) at risk of recurrence; however, evidence, including all stages of the disease, is inconclusive. A meta-analysis was conducted to assess the efficacy of postoperative treatment with or without TSH inhibition in Chinese patients who had undergone surgery for DTC.

Methods

PubMed (MEDLINE), Embase, and two Chinese databases (Wanfang and China National Knowledge Infrastructure) were searched for relevant studies published from inception to 1 April 2023. Study characteristics, patient characteristics, and recurrence or metastasis data were extracted. Data from 20 prospective studies were pooled for overall effect and for effects by tum

SUBMITTER: Ming J 

PROVIDER: S-EPMC12552556 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature