Pleomorphic adenoma with extensive oncocytic change in the parotid gland: a case report and review.

ABSTRACT:

Background

Pleomorphic adenoma (PA) is the most common benign tumor of the salivary glands, but rarely shows extensive oncocytic metaplasia. Extensive oncocytic metaplasia within PA is rarely encountered and may closely mimic malignant neoplasms, creating significant diagnostic challenges for clinicians and pathologists. This uncommon histologic variant can potentially influence clinical decision-making processes and subsequent patient management strategies.

Case description

A 54-year-old male presented with a painless, slowly enlarging mass in the left parotid gland, which had persisted for two years. Imaging studies revealed a poorly demarcated 2.6 cm mass involving both the superficial and deep lobes of the parotid gland. Fine needle aspiration biopsy suggested oncocytic

SUBMITTER: Choi JY 

PROVIDER: S-EPMC12552580 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature