Cost-Effectiveness and Evidence Gaps Surrounding PSMA-PET for Recurrent Prostate Cancer Evaluation.

ABSTRACT:

Importance

Prostate-specific membrane antigen positron emission tomography (PSMA-PET), a form of molecular imaging, increases detection of advanced and metastatic prostate cancer, but its potential to increase treatment costs due to increased detection is poorly defined.

Objective

To estimate lifetime health and cost outcomes and evaluate the cost-effectiveness associated with implementing PSMA-PET in the clinical evaluation of a patient with a biochemical recurrence (BCR) of prostate cancer, with evaluation of sources of uncertainty in the underlying evidence and assessment of the need and focus of additional data collection.

Design, setting, and participants

This economic evaluation developed a decision-analytic model consisting of a decision tree and a Markov model

SUBMITTER: Kunst N 

PROVIDER: S-EPMC12552925 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature