Social Vulnerability Associations With Hypopharyngeal Carcinoma Treatment and Prognostic Disparities.

ABSTRACT:

Objectives

Prior studies investigating the impacts of social determinants of health (SDoH) on hypopharyngeal cancer have only assessed the impact of individual factors on patient outcomes. This study uses the CDC's Social Vulnerability Index (SVI) and a national patient cohort to examine how the interrelational influence of SDoH affect hypopharyngeal cancer prognosis, treatment, and follow-up.

Methods

This retrospective cohort study analyzed patients from 1975 to 2017 with a diagnosis of hypopharyngeal carcinoma in the NCI-SEER database. Net social vulnerability and its contributions from 15 SDoH variables were ranked and scored across all US counties, yielding a SVI. SVI scores were matched to the patient's county of residence, and univariate linear regressions were perform

SUBMITTER: Cuenca CM 

PROVIDER: S-EPMC12553032 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature