The association between serum HbA1c and infected pancreatic necrosis in acute necrotizing pancreatitis.

ABSTRACT:

Background

Given the evidence that poor glycemic control is associated with immunological dysfunction, serum glycosylated hemoglobin A1c (HbA1c), as a useful indicator reflecting blood glucose homeostasis, has potential to predict infectious complications. In this study, we aimed to explore the association between poor glycemic control (HbA1c ≥ 6.5 as an indicator) and infected pancreatic necrosis (IPN) in patients with acute necrotizing pancreatitis (ANP).

Methods

This is a secondary analysis of pooled data from the TRACE trial and a retrospective single-center cohort, involving ANP patients admitted within 72 h after onset of abdominal pain between March 2017 and October 2022. Patients had no HbA1c data at enrollment/admission were excluded. The Multivariable Cox proportio

SUBMITTER: Wang X 

PROVIDER: S-EPMC12553147 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature