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Establishing optimal cut-offs of cardio-metabolic indices for diagnosing metabolic syndrome in type 2 diabetes.


ABSTRACT:

Background

This study aimed to determine the optimal cut-off values of various cardio-metabolic indices for predicting MetS in Iranian adults with T2DM.

Methods

This cross-sectional analytical study included 400 Iranian adults with T2DM. Anthropometric and biochemical parameters were assessed, including body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), lipid profile, fasting blood glucose (FBG), and blood pressure. Several cardio-metabolic indices-including the cardio-metabolic index (CMI), lipid accumulation product (LAP), and atherogenic index of plasma (AIP)-were calculated. Receiver operating characteristic (ROC) curve analysis was used to determine optimal cut-off points, sensitivity, and specificity of these indices for MetS diagnosis.

Resul

SUBMITTER: Bazyar H 

PROVIDER: S-EPMC12553255 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature