Cardiopulmonary Exercise Testing for Characterization of Hypertrophic Cardiomyopathy: A Meta-Analysis.

ABSTRACT:

Background

Hypertrophic cardiomyopathy (HCM) is associated with substantial risk of adverse cardiac events. Consequently, detailed physiologic assessment and accurate risk stratification in HCM are of high clinical importance. This systematic review and meta-analysis synthesizes current evidence on the utility of cardiopulmonary exercise testing (CPET) for characterization and prognostication of HCM.

Methods

PubMed, Embase, Scopus, and Web of Science were systematically searched for eligible studies from database inception to November 2023. The primary outcome of mortality was assessed using meta-analyzed hazard ratios (HRs) and 95% confidence intervals (CIs) from Cox proportional hazard models.

Results

Sixty full-length articles focusing on CPETs performed in patient

SUBMITTER: Landsteiner I 

PROVIDER: S-EPMC12553425 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature