Inflammatory Status Modifies the Association Between Glycemic Traits and Cognitive Impairment in Patients With Coronary Artery Disease.

ABSTRACT:

Background

The evidence regarding the modifying role of inflammation in the association between glycemic traits and cognitive impairment remains insufficient. This study aimed to explore the association between glycemic traits and mild cognitive impairment (MCI) in patients with coronary artery disease (CAD), with particular emphasis on whether this association is influenced by varying levels of inflammation.

Methods

This cross-sectional study included 1437 patients with CAD who underwent cognitive function assessment during hospitalization. Cognitive function was assessed using the Mini-Mental State Examination and the Montreal Cognitive Assessment to identify patients with MCI. The hsCRP (high-sensitivity C-reactive protein) level>3 mg/L was defined as high inflammatory ri

SUBMITTER: Feng L 

PROVIDER: S-EPMC12553436 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature