Sex Differences in the Impact of Atherosclerotic Cardiovascular Risk Burden on Cognitive Health.

ABSTRACT:

Background

Sex affects the prevalence of atherosclerotic cardiovascular disease (ASCVD) risk factors but whether sex differences exist in the associations between ASCVD risk burden and cognitive function is unclear.

Methods

This cross-sectional study included participants from a population-based cohort study in China that recruited community-dwelling adults aged 50 to 75 years without baseline cardiovascular disease and stroke. The 10-year ASCVD risk burden was quantified with 3 multivariate risk prediction equations. Cognitive domains of memory, attention, visuospatial function, executive function, and processing speed were assessed. Multivariable linear regression models were used to examine the interaction terms between sex and ASCVD risk scores on cognition.

Results</

SUBMITTER: Zuo L 

PROVIDER: S-EPMC12553448 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature