Effectiveness of Individual Cognitive Stimulation on Cognition in Mild Alzheimer's Disease: A Multicenter RCT.

ABSTRACT:

Background

Alzheimer's Disease (AD) is characterised by impairments across several neurocognitive domains, including memory and executive function. The study explored the effectiveness of a 3-month individual Cognitive Stimulation (iCS) program in older adults with mild AD.

Methods

A multicenter randomised controlled trial was conducted with 62 Portuguese older adults with mild AD. Participants were randomly assigned to either iCS (n = 33; 53%) or treatment as usual (TAU, n = 29; 47%). Cognitive outcomes were assessed at baseline, post-intervention, and 12-week follow-up using standardised tests for global cognition, memory and executive function.

Results

The iCS group showed a significant improvement in memory and executive function compared to the TAU group. The ana

SUBMITTER: Justo-Henriques SI 

PROVIDER: S-EPMC12554431 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature