Circular RNA hsa_circ_0006522 correlates with unfavorable prognosis and promotes the proliferative, migrative, and invasive abilities of breast cancer cells.

ABSTRACT:

Background

Breast cancer persists as a predominant oncology burden impacting women globally. It is of utmost importance to explore new therapeutic targets that can boost recovery rates and enhance the long-term survival of breast cancer patients. Recently, emerging evidence substantiates circular RNAs as pivotal mediators orchestrating breast carcinogenesis. We aimed to evaluate the role of circular RNA hsa_circ_0006522 on breast cancer behavior in vitro.

Methods

In this study, we utilized fluorescence in situ hybridization (FISH) and tissue microarray techniques to examine the expression of hsa_circ_0006522 in breast cancer tissues. Subsequently, we carried out a comprehensive analysis of the correlation between the expression level of hsa_circ_0006522 in breast canc

SUBMITTER: Wang X 

PROVIDER: S-EPMC12554460 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature