Cost-Effectiveness of Family Conferences to Reduce Polypharmacy in Frail Older Adults.

ABSTRACT:

Background

Cost-effectiveness of family conferences on deprescribing with joint prioritization of treatment goals in primary care has not been investigated so far. We assessed cost-effectiveness in the cluster-randomized controlled COFRAIL trial conducted with general practitioners and 521 older frail patients with polypharmacy cared for at home in Germany.

Methods

Hospital admissions averted and quality-adjusted life years (QALYs) gained were associated with costs from the German Social Insurance perspective. We applied adjusted GLM regressions with specified distributions to estimate group differences on imputed data, plotted bootstrap cost-outcome pairs by simulated resampling of the study population to illustrate uncertainty and calculate the probability of cost-effectiv

SUBMITTER: Montalbo J 

PROVIDER: S-EPMC12554836 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature