Impact of respiratory viruses detection on outcomes in ventilated nosocomial pneumonia: an exposed/unexposed study.

ABSTRACT:

Introduction

Ventilator-associated pneumonia (VAP) and ventilated hospital-acquired pneumonia (vHAP) are major causes of morbidity and mortality in intensive care unit (ICU) patients. The role of viral co-infections in these conditions is an emerging area of interest; however, their impact on clinical outcomes remains poorly understood. This study aimed to assess the effect of viral detection on mortality and other clinical outcomes in patients with bacterial vHAP/VAP.

Materials and methods

We conducted a retrospective analysis of patients diagnosed with bacterial vHAP or VAP in a tertiary ICU between 2020 and 2024. All patients underwent distal respiratory sampling with quantitative culture and multiplex PCR (mPCR) testing for respiratory viruses (Biofire FilmArray Pneumoni

SUBMITTER: Do Rego H 

PROVIDER: S-EPMC12554854 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature