The British Society for Antimicrobial Chemotherapy Resistance Surveillance Project: methods and limitations.

ABSTRACT:

Objectives

The BSAC Bacteraemia and Respiratory Resistance Surveillance Programmes provided long-term surveillance of antibiotic resistance in key pathogens of bloodstream and both community- and hospital-acquired respiratory infections in the UK and Ireland. This paper details the methodologies used. Data limitations are discussed.

Methods

Sentinel laboratories across the UK and Ireland contributed up to a fixed annual quota of isolates of defined bacterial groups. For each Programme, a Central Laboratory confirmed bacterial identifications, measured MICs by the BSAC agar dilution method, investigated mechanisms of resistance and determined serotypes of Streptococcus pneumoniae. Identification methods evolved over time, e.g. with adoption of MALDI-TOF. Classification of sus

SUBMITTER: Allen M 

PROVIDER: S-EPMC12555735 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature