Overt hepatic encephalopathy after elective and preemptive TIPS: Risk factors and prognosis.

ABSTRACT:

Background & aims

Overt hepatic encephalopathy (OHE) develops in 30-50% of patients after transjugular intrahepatic portosystemic shunt (TIPS) placement, depending on patient characteristics and TIPS indication. Data on OHE after preemptive TIPS (pTIPS) are limited. We aimed to assess the prevalence of OHE after pTIPS, to compare OHE after pTIPS and elective TIPS, and to identify risk factors for OHE in each clinical situation.

Methods

We performed a single-center observational study of consecutive patients with cirrhosis treated with pTIPS or elective TIPS between 2017 and 2023. Patients were followed until 1 year, death, or liver transplantation (LT).

Results

A total of 191 patients were included (pTIPS 85, elective TIPS 106). Patients treated with pTIPS were signif

SUBMITTER: Rudler M 

PROVIDER: S-EPMC12557589 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature