Survival of patients with node-negative lung cancer and chest wall invasion.

ABSTRACT:

Background

Patients with T3 non-small cell lung cancer (NSCLC) with chest wall invasion (CWI) have poorer survival than patients with T3 NSCLC defined by other T3 descriptors, but their survival has not been compared with patients with T4 NSCLC. Our objective was to compare the survival of patients with NSCLC with CWI, currently a T3 descriptor, with that of patients with T4 NSCLC.

Methods

A retrospective analysis was conducted of the National Cancer Database (NCDB) comparing patients diagnosed with node-negative NSCLC <7 cm with CWI to those diagnosed with cT4N0M0 NSCLC from 2010-2015. A 1:1 propensity match was performed. Demographics, comorbidities, and tumor characteristics were compared utilizing chi-squared and Wilcoxon rank-sum tests. Kaplan-Meier analysis was used to

SUBMITTER: Singh A 

PROVIDER: S-EPMC12557622 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature