Long-term mortality in patients who survive surgery for infective endocarditis versus the background population: a nationwide study.

ABSTRACT:

Background

Valvular surgery for infective endocarditis (IE) can improve survival but carries substantial risk. Limited data exist on long-term outcomes for patients who survive surgery compared with a background population. We aim to compare long-term mortality and morbidity in patients with IE, who survive 90-days following valvular surgery to a matched Danish background population.

Methods

Using Danish registries, we identified patients who survived >90 days post-valvular surgery for first-time IE (2010-2023). Each patient was matched 1:3 with controls from the background population by age, sex and selected comorbidities. All-cause mortality was assessed at 5 and 10 years using the Kaplan-Meier estimator and the multivariate Cox model. Further, we examined the time spent i

SUBMITTER: Nielsen ST 

PROVIDER: S-EPMC12557802 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature