The relationship between frailty and multimorbidity in Chinese older adults: the chain mediating effects of sleep quality and anxiety.

ABSTRACT:

Background

Previous studies have shown an association between frailty and multimorbidity, but the underlying mechanisms are still unclear. Therefore, this study aimed to investigate the potential chain mediating roles of sleep quality and anxiety in the relationship between frailty and multimorbidity.

Methods

This cross-sectional study used data from the first follow-up of the Liyang cohort study on chronic diseases and risk factors monitoring in China (Liyang Study), which comprised 2874 participants aged ≥ 60 years from 17 health centres in Liyang City. Multimorbidity was defined based on 13 self-reported chronic conditions. A modified version of the frailty phenotype was used to assess frailty. Sleep quality and anxiety were assessed using the Pittsburgh Sleep Quality Ind

SUBMITTER: Ma Z 

PROVIDER: S-EPMC12557892 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature