Nurse-led evidence-based protocolized weaning for invasive mechanical ventilation patients in the ICU: a hybrid type 1 effectiveness-implementation study.

ABSTRACT:

Background

Prolonged invasive mechanical ventilation (IMV) increases risks of complications and healthcare burdens. Protocol-directed weaning reduces IMV duration but faces implementation barriers. Nurse-led protocolized weaning (NLPW) offers promise, yet evidence on its effectiveness within specific healthcare contexts and systematic implementation processes remains limited.

Objectives

This hybrid type 1 effectiveness-implementation study evaluated the clinical impact and feasibility of implementation of a structured NLPW program in a surgical ICU.

Methods

A mixed-methods design was employed. Quantitative component: A quasi-experimental study with historical controls compared patient outcomes (weaning duration, IMV duration, ICU stay, 24-hours reintubation) before (M

SUBMITTER: Xue L 

PROVIDER: S-EPMC12557896 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature