Associations of early-adulthood adiposity with breast parenchymal tissue complexity within premenopausal women.

ABSTRACT:

Background

Early-adulthood adiposity is associated with breast cancer risk. This study aims to evaluate the associations of early-adulthood adiposity with an emerging biomarker of breast cancer risk, breast parenchymal complexity, within premenopausal women.

Methods

We retrospectively analyzed early-adulthood adiposity data and screening digital mammograms (DMs) of 326 premenopausal women (age in years; median: 48; range: 34-58) recruited at our institution. Adiposity measures were either assessed by trained personnel or self-reported by participants. DMs were analyzed using a well-validated computational imaging pipeline consisting of automated breast segmentation and radiomic feature extraction modules. The extracted radiomic features were fused into woman-specific breast

SUBMITTER: Das Gupta S 

PROVIDER: S-EPMC12557909 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature