Efficacy of Diet on Quality of life in Multiple Sclerosis (EDQ-MS): a study protocol for a randomized controlled clinical trial.

ABSTRACT:

Background

The primary objective of this study is to evaluate the efficacy of two dietary interventions, time-restricted olive oil-based (TROO) ketogenic and modified Paleolithic elimination (MPE), compared to usual care control group receiving Dietary Guidelines for Americans (DGA) resources, on quality of life (QoL) among individuals with relapsing-remitting multiple sclerosis (RRMS). The secondary objectives are to evaluate the long-term effects on functional disability, fatigue, mood, motor, ocular and cognitive function, and disease activity.

Methods

The proposed study will consist of 162 study participants attending 3 in-person site visits at months 0, 3, and 24, with online surveys every 3 months. This study will use a randomized, single-blind, controlled design to in

SUBMITTER: Shemirani F 

PROVIDER: S-EPMC12557952 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature