Functional alterations across motor, visual, and attention cerebellar and cortical networks in patients with asymptomatic spinal cord compression.

ABSTRACT:

Objective

The goal of this study was to investigate the patterns of functional connectivity (FC) in patients with asymptomatic cervical spinal cord compression and determine how the patterns differ from those in healthy controls and correlate with spinal compression and Neck Disability Index (NDI) scores.

Methods

This cross-sectional study consisted of 45 patients with asymptomatic spinal cord compression (ASCC) and 35 healthy controls (HCs) with resting-state functional MRI (rs-fMRI) scans. The patients with ASCC also had sagittal and axial T2-weighted cervical spine MRI scans. The rs-fMRI scans were used for region of interest to region of interest analyses that generated brain networks of FC that could be compared between and within groups.

Results

The patients wit

SUBMITTER: Kostiuk A 

PROVIDER: S-EPMC12558012 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature