Association between hemoglobin-to-red blood cell distribution width ratio and mortality in critically Ill patients with aortic dissection: A retrospective cohort study from MIMIC-IV database.

ABSTRACT: This study aims to reveal the correlation between the hemoglobin-to-red cell distribution width ratio (HRR) and mortality among the patients with aortic dissection (AD). We identified critically ill patients with AD in MIMIC-IV database. The optimal cutoff value of HRR was calculated through ROC curve analysis conducted by using the maximum Youden index for the prediction of survival status. The primary outcome was 30-day mortality, with 90-day and 365-day all-cause mortality as secondary outcomes. The Cox proportional hazard regression models were utilized to analyze the association between baseline HRR and mortality. Restricted cubic splines analysis was utilized to determine the relationship curve between mortality and the HRR level and examine the threshold saturation effect. We furthe

SUBMITTER: Li X 

PROVIDER: S-EPMC12558236 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature