Combined effects of residual cholesterol inflammatory index and triglyceride-glucose-BMI on risk of cardio-cerebrovascular disease: A cohort study.

ABSTRACT: This study aimed to analyze the impact of the residual cholesterol inflammatory index (RCII) and the triglyceride-glucose-body mass index (TyG-BMI) on the risk of cardio-cerebrovascular disease (CCVD). Data were obtained from the China Health and Retirement Longitudinal Study, and participants were categorized into 4 groups based on optimal cutoff values of RCII and TyG-BMI. The influence of RCII, TyG-BMI, and their combination on CCVD was assessed using Cox proportional hazards regression and Kaplan-Meier survival models. A total of 7677 individuals were included. Both higher RCII and higher TyG-BMI were independently associated with increased risk of CCVD. Importantly, the combined elevation of RCII and TyG-BMI showed the highest risk (HR = 1.47, 95% CI = 1.21-1.78, P < .05), whereas ele

SUBMITTER: Yang H 

PROVIDER: S-EPMC12558257 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature