Common Themes and Uncertainties in Management of Secondary Polycythaemia: An International Clinician Survey of Practice.

ABSTRACT:

Introduction

Secondary and idiopathic polycythaemia is far more common than polycythaemia vera. Whilst venesection for polycythaemia vera has a robust evidence base, the data supporting this treatment for secondary and/or idiopathic polycythaemia are limited to small single-arm studies showing transient improvement in symptoms or physiologic endpoints. As a result the British Society for Haematology Guideline for the management of specific situations in polycythaemia vera and secondary erythrocytosis suggests considering venesection in patients with hypoxic lung disease with Hct > 0.56 or to a target Hct < 0.55 in those with idiopathic polycythaemia. We hypothesised that this paucity of evidence results in widespread variation in management of secondary polycythaemia.

Met

SUBMITTER: Lr Nicolson P 

PROVIDER: S-EPMC12558438 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature