Survival outcomes and prognostic factors in children and adults with medulloblastoma from a Latin America country: A retrospective cohort.

ABSTRACT:

Background

Few studies have evaluated the real-world outcomes of patients with medulloblastoma with contradictory results. Therefore, we aimed to compare the characteristics, survival outcomes, and prognostic factors between children and adults with medulloblastoma.

Methods

We conducted a retrospective cohort study in a single academic center between 2000 and 2016. Patients were categorized into children and adolescents (≤19 years) and adults (>19 years). Overall survival (OS) and disease-free survival (DFS) were estimated with the Kaplan-Meier method. Prognostic factors were determined using Cox models.

Results

In total, 173 patients were included (79 adults and 94 children). No differences were observed in clinical characteristics according to age groups. At 5 years

SUBMITTER: Mallouh M 

PROVIDER: S-EPMC12558496 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature