Associations between day of admission, admission hyponatremia and hospital outcomes in medical patients: A retrospective multicenter cohort study.

ABSTRACT:

Introduction

We investigated the relationship between admission day, serum sodium concentration, and outcomes in medical inpatients. Hyponatremia, the most common electrolyte abnormality in hospitalized adults, is associated with prolonged hospital length of stay (LOS) and higher mortality. Weekend admissions are also linked to worse outcomes, but the magnitude of this "weekend effect" may vary with diagnoses and particular day of admission.

Design

Retrospective multicenter cohort study.

Setting

Four Ministry of National Guard - Health Affairs hospitals in Saudi Arabia (January 1, 2016 - May 9, 2022).

Participants

43,361 adult medical admissions. Patients with hypernatremia (n = 1,892) or LOS > 30 days (n = 2,988) were excluded.

Interventions

Admissions

SUBMITTER: Rajendram R 

PROVIDER: S-EPMC12558553 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature