Inhibitory control deficits in borderline personality disorder: a meta-analysis of stop-signal and Go/No-Go tasks.

ABSTRACT:

Background

Impulsivity, a multifaceted construct, is a core feature of borderline personality disorder (BPD), associated with functional impairment and suicide mortality. Findings on motor inhibitory control, a key dimension of impulsivity, in BPD are heterogeneous.

Methods

This PRISMA-guided meta-analysis examines motor inhibitory control in adults with BPD compared to healthy controls (HCs), using Stop-Signal Task and Go/No-Go Task data. Thirty-seven datasets from 35 articles were included.

Results

Results from random-effect models suggest that BPD patients exhibit significantly higher motor inhibitory control deficits than HCs, with a small to moderate effect size. Contrary to common assumptions, a mixed-model effect found that emotional factors did not moderate in

SUBMITTER: Barakat N 

PROVIDER: S-EPMC12558629 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature