Right Atrial Myxoma in a Young Patient with a DSG-2 Genetic Mutation: A Case Report.

ABSTRACT:

Introduction

Primary heart tumours, particularly right atrial myxomas, are exceedingly rare. We present a particularly unique case of a young patient who was found to have a right atrial myxoma while carrying a desmoglein-2 (DSG-2) gene splice-site variant, a mutation typically associated with cardiomyopathies but not previously reported concomitantly with atrial myxoma development.

Case presentation

A young male in his twenties presented with constitutional symptoms, including dizziness and palpitations. An echocardiogram showed a 3.5-4 cm right atrial mass originating from the right atrium-superior vena cava junction. Surgical excision via midline sternotomy and right atriotomy was performed without complications. Histopathology confirmed a benign atrial myxoma. Given the

SUBMITTER: Attard SP 

PROVIDER: S-EPMC12558662 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature