The role of pan-immune-inflammation index in the prognosis of Chinese cases with triple-negative breast cancer following surgical resection.

ABSTRACT:

Background

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer associated with high recurrence rates and poor survival outcomes. Growing evidence suggests that systemic inflammation plays a critical role in tumor progression and immune evasion. The pan-immune-inflammation value (PIV), a composite index derived from peripheral blood counts, has emerged as a potential biomarker of host immune and inflammatory status.

Objective

This study aimed to evaluate the prognostic value of preoperative PIV in Chinese cases with TNBC following curative surgical resection.

Methods

We conducted a retrospective cohort study of 312 TNBC cases treated at a tertiary center in China between January 2015 and March 2020. PIV was calculated as (neutrophil count × p

SUBMITTER: Qi M 

PROVIDER: S-EPMC12558987 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature