Correcting for the Inflated Adult Population Denominator in an English Nationwide Health Care Cohort: Database Analysis Study.

ABSTRACT:

Background

Electronic health care databases are widely used for epidemiological studies. However, they may contain inactive records of individuals no longer participating in the health care system. These inactive records create a methodological challenge as they systematically appear as unexposed with no recorded outcomes. Given the widespread health care system engagement during the COVID-19 pandemic, the English National Health Service (NHS), which hosts a national pandemic planning and research dataset with linkage to COVID-19 vaccination and emergency care data, makes it an ideal setting to identify the extent of overrepresentation due to inactive health care records and assess ways to mitigate them.

Objective

The objective of this study is to report any differences betw

SUBMITTER: Venkatesan S 

PROVIDER: S-EPMC12559012 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature