4D flow MRI-based grading of left ventricular diastolic dysfunction: a validation study against echocardiography.

ABSTRACT:

Objectives

To assess the feasibility and accuracy of 4D flow MRI-based grading of left ventricular diastolic dysfunction, using echocardiography as the reference method.

Methods

Between October 2016 and February 2022, subjects were prospectively recruited for transthoracic echocardiographic evaluation of left ventricular diastolic function and 4D flow MRI at 3 T. Echocardiographic grading of diastolic dysfunction was performed according to the multiparametric, threshold-based 2016 ASE/EACVI approach. Volumetric and echo-equivalent peak velocity grading parameters were evaluated from 4D flow magnitude and velocity data, respectively. Duration of vortical blood flow along the main pulmonary artery (t_vortex) was employed as a surrogate grading parameter for echocardi

SUBMITTER: Reiter C 

PROVIDER: S-EPMC12559040 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature