Measuring Fatigue in Multiple Sclerosis: A Rapid Review.

ABSTRACT:

Background

Fatigue is one of the most prevalent and debilitating symptoms of multiple sclerosis (MS), as people with MS describe it. It has a complex pathogenesis and often precedes the clinical symptoms of MS and potentially indicates disease progression. Given its prevalence, impact, and intricate connections to disease pathology, accurate measurement is crucial to manage and study fatigue in people with MS; however, current measurements often lack content validity. A mismatch between key aspects of fatigue and existing fatigue scales will limit these scales' ability to capture the full scope of MS-related fatigue. We aimed to examine the current evidence on MS-related fatigue to define key aspects of fatigue in the literature and compare them with the scales used to measure MS-r

SUBMITTER: Namsrai T 

PROVIDER: S-EPMC12559044 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature